反应详情

To stirred solution of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol (4 g, 0.02 mol) in dichloromethane (20 ml), isopropyl ether hydrochloride (6 ml) was added at ambient temperature and stirred for 30 minutes. Solvents were distilled off from the reaction mixture. To the residue isopropyl ether (8 ml) was added and stirred for 15 minutes. Solvent was distilled off from the mixture to give 4.3 g of the title compound.

1. additionwas added at ambient temperature
2. distillationSolvents were distilled off from the reaction mixture
3. additionTo the residue isopropyl ether (8 ml) was added
4. stirringstirred for 15 minutes
5. distillationSolvent was distilled off from the mixture