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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1040354Generated: November 2, 2026

2-(3-(Benzyloxy)-4-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → Methyl 3''-(benzyloxy)-4''-chloro-2,6-dimethoxy-1,1':2',1''-terphenyl-4'-carboxylate

https://huagongshe.com/reaction/1040354

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-(Benzyloxy)-4-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 59846881—
ReactantMethyl 2-bromo-2',6'-dimethoxybiphenyl-4-carboxylateHCID 66721235—
ProductMethyl 3''-(benzyloxy)-4''-chloro-2,6-dimethoxy-1,1':2',1''-terphenyl-4'-carboxylateHCID 6672110445.1%

Reaction Steps

According to the method described in example 10.2, starting from 2.79 g (7.94 mmol) of methyl 2-bromo-2′,6′-dimethoxybiphenyl-4-carboxylate and 3.28 g (9.53 mmol) of 2-[3-(benzyloxy)-4-chlorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, we obtain 1.75 g of methyl 3″-(benzyloxy)-4″-chloro-2,6-dimethoxy-1,1′:2′,1″-terphenyl-4′-carboxylate in the form of oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08552201B2
Source datasetuspto-grants-2013_10
ORD IDord-d3054f920e3c405296bb968fa095477e
Source noteuspto-grants-2013_10