HRID1040531

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[C@@]1(Cc2ccc(C#N)cc2)C(=O)N(c2cc(Cl)cc(Cl)c2)c2ncc(C(=O)O)n21

HCID58430912

未命名化合物

结构：C[C@@]1(Cc2ccc(OC(F)(F)F)cc2)C(=O)N(c2cc(Cl)cc(Cl)c2)c2ncc(C(=O)O)n21

HCID58431229

未命名化合物

PRODUCTS

生成物

结构：C[C@H](NC(=O)c1cnc2n1[C@](C)(Cc1ccc(C#N)cc1)C(=O)N2c1cc(Cl)cc(Cl)c1)C(=O)NCc1ccccc1

HCID58431153

未命名化合物

PROCEDURE

实验过程

The following compounds were prepared using procedures similar to those described above using either (R)-5-(4-Cyano-benzyl)-7-(3,5-dichloro-phenyl)-5-methyl-6-oxo-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid or (R)-7-(3,5-Dichloro-phenyl)-5-methyl-6-oxo-5-(4-trifluoromethoxy-benzyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid as a starting material:

WORKUP

后处理

customThe following compounds were prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-34a43a1464d94bd5abf631e1e80e3f0d
来源数据集: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08552205B2
来源说明: uspto-grants-2013_10

反应 SMILES

[C:1]([C:3]1[CH:30]=[CH:29][C:6]([CH2:7][C@@:8]2([CH3:28])[N:12]3[C:13]([C:16](O)=[O:17])=[CH:14][N:15]=[C:11]3[N:10]([C:19]3[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([Cl:26])[CH:20]=3)[C:9]2=[O:27])=[CH:5][CH:4]=1)#[N:2].ClC1C=C(N2C3=NC=C(C(O)=O)N3[C@](C)([CH2:50][C:51]3[CH:56]=[CH:55][C:54](OC(F)(F)F)=[CH:53][CH:52]=3)C2=O)C=C(Cl)C=1>>[CH2:50]([NH:10][C:9]([C@@H:8]([NH:12][C:16]([C:13]1[N:12]2[C@@:8]([CH2:7][C:6]3[CH:29]=[CH:30][C:3]([C:1]#[N:2])=[CH:4][CH:5]=3)([CH3:28])[C:9](=[O:27])[N:10]([C:19]3[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([Cl:26])[CH:20]=3)[C:11]2=[N:15][CH:14]=1)=[O:17])[CH3:7])=[O:27])[C:51]1[CH:52]=[CH:53][CH:54]=[CH:55][CH:56]=1