HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sarcosine → HCID 67389857, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sarcosine | HCID 1088 | — |
| Reactant | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Reactant | Methanesulfonamide | HCID 72879 | — |
| Reactant | HCID 58430957 | HCID 58430957 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Product | HCID 67389857 | HCID 67389857 | — |
Reaction Steps
(R)-5-(4-Cyano-benzyl)-7-(3,5-dichloro-phenyl)-5-methyl-6-oxo-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid {1-[1-(4-iodo-pyridin-2-yl)-cyclopropylcarbamoyl]-cyclopropyl}-amide (50 mg, 0.065 mmol), methanesulfonamide (7.4 mg, 0.078 mmol), sarcosine (1.2 mg, 0.13 mmol), copper (I) iodide 0.76 mg, 0.004 mmol) and potassium phosphate (33.9 mg, 0.126 mmol) were combined in a Biotage microwave tube and flushed with Ar. The reaction was diluted with DMF and sealed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08552205B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-ec2f64e9810643dfb7e00ff3d0c9b031 |
| Source note | uspto-grants-2013_10 |