HCID 67264557, compound → HCID 67264564, compound

Participants

Reaction Steps

1-(4-Nitro-3-pyrazol-1-yl-phenyl)-piperidine-4-carboxylic acid ethyl ester was treated under standard hydrogenation conditions (H2, EtOH, 10% Pd/C) to yield desired 1-(4-Amino-3-pyrazol-1-yl-phenyl)-piperidine-4-carboxylic acid ethyl ester as a glass, which was used for the subsequent reaction without further purification; TLC: 1:1 EtOAc/Hexane Rf 0.5, homogeneous; LC/MS (m/e) 315.28 (M+H).

Provenance & Evidence