HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethyl borate → 4-(Difluoromethoxy)benzeneboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethyl borate | HCID 8470 | — |
| Reactant | 1-(Difluoromethoxy)-4-iodobenzene | HCID 2737008 | — |
| Reactant | HCID 178418918 | HCID 178418918 | — |
| Product | 4-(Difluoromethoxy)benzeneboronic acid | HCID 23082146 | — |
Reaction Steps
In a departure from the procedure described above the compound is prepared from 4-difluoromethoxy-1-iodo-benzene using iPrMgCl to generate the arylmetal compound and trapping this intermediate with trimethyl borate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557782B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-67c58d6972964c7cbe27d05bbc8b83d6 |
| Source note | uspto-grants-2013_10 |