HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-5-isoxazolecarboxylic acid → 3-(6-Chloro-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)-5-methylisoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-5-isoxazolecarboxylic acid | HCID 76947 | — |
| Reactant | 1-Chloro-4-hydrazinophthalazine | HCID 2793752 | — |
| Product | 3-(6-Chloro-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)-5-methylisoxazole | HCID 18427539 | — |
Reaction Steps
Intermediate 14b was prepared in two steps from intermediate 11 in an analogous fashion to the preparation of intermediate 14a (see Example 1). Commercially available 5-methylisoxazole-3-carboxylic acid (12c) was used in the first step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557815B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-f3d7ee1e86bb4017898ed1eb00956112 |
| Source note | uspto-grants-2013_10 |