反应详情

To a solution of 2-[(methylsulfonyl)methyl]-5-[4-nitro-3-(tetrahydro-2H-pyran-4-yloxy)phenoxy]pyridine (22 g) in ethanol (250 mL) was added 10% palladium carbon (2 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for 15 hr. Palladium carbon was removed, and the residue was concentrated under reduced pressure to give the title compound (20 g, yield 100%) as a colorless amorphous solid.

1. customPalladium carbon was removed
2. concentrationthe residue was concentrated under reduced pressure