Sodium Hydroxide → HCID 58173125, compound

HRID 1042327Notes

Reaction equation

HRID 1042327 reaction equation
[CH3:1][NH:2][C:3]([C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[N:11]=[CH:10][C:9]([C:15]([O:17]CC)=[O:16])=[C:8]2[NH:20][C:21]1[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=1)=[O:4].[OH-].[Na+]>>[CH3:1][NH:2][C:3]([C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[N:11]=[CH:10][C:9]([C:15]([OH:17])=[O:16])=[C:8]2[NH:20][C:21]1[CH:22]=[CH:23][C:24]([CH3:27])=[CH:25][CH:26]=1)=[O:4]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 24970349HCID 24970349, compound

Product 1

HCID 58173125HCID 58173125, compound

Procedure

Ethyl 6-(methylcarbamoyl)-4-[(4-methylphenyl)amino]quinoline-3-carboxylate was hydrolysed under basic conditions using NaOH (aq.). The final product was purified by column chromatography.

Workup

  1. customThe final product was purified by column chromatography

Sources & evidence

ORD record
ord-beb01614a1ab45699fbb9a5bab3b5ff5
Source dataset
uspto-grants-2013_10
Patent number
US08557843B2

Reaction notes

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