HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → 2-Ethoxy-4-(trifluoromethyl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | N-methoxy-N-methyl-2-ethoxy-4-trifluoromethyl-benzamide | HCID 86649957 | — |
| Product | 2-Ethoxy-4-(trifluoromethyl)benzaldehyde | HCID 22494338 | 89.1% |
Reaction Steps
N-Methoxy-N-methyl-2-ethoxy-4-trifluoromethyl-benzamide (1.04 g) was reacted with 1 M LAH (1 ml) at −40° C. for 2 hrs as described above to yield title compound (729 mg, 65%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557872B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-c2788596af4a4dd391b226db3bbe9fb4 |
| Source note | uspto-grants-2013_10 |