HCID 86649958, compound → 2-amino-N-methoxy-N-methyl-4-trifluoromethyl-benzamide

HRID 1042462Notes

Reaction equation

HRID 1042462 reaction equation
[CH3:1][O:2][N:3]([CH3:19])[C:4](=[O:18])[C:5]1[CH:10]=[CH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[CH:7][C:6]=1[N+:15]([O-])=O>[Pd]>[NH2:15][C:6]1[CH:7]=[C:8]([C:11]([F:12])([F:13])[F:14])[CH:9]=[CH:10][C:5]=1[C:4]([N:3]([O:2][CH3:1])[CH3:19])=[O:18]

Participants

3

Reactant 1

HCID 86649958HCID 86649958, compound

Product 1

HCID 866499592-amino-N-methoxy-N-methyl-4-trifluoromethyl-benzamide

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

N-Methoxy-N-methyl-2-nitro-4-trifluoromethyl-benzamide (2.54 g, 9.12 mmol) was reacted with Pd/C (441 mg) under hydrogen atmosphere as described above to yield title compound.

Sources & evidence

ORD record
ord-8b2337c6cad04bbabd764924b0fb3500
Source dataset
uspto-grants-2013_10
Patent number
US08557872B2

Reaction notes

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