HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 3-(2-Butoxy-4-trifluoromethyl-phenyl)-acrylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | 3-(2-Butoxy-4-trifluoromethyl-phenyl)-acrylic acid methyl ester | HCID 66855719 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(2-Butoxy-4-trifluoromethyl-phenyl)-acrylic acid | HCID 66855592 | — |
Reaction Steps
3-(2-Butoxy-4-trifluoromethyl-phenyl)-acrylic acid methyl ester (464 mg) was reacted with 1N LiOH (10 ml) in THF and CH3OH for 1 hr as described above to yield title compound
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557872B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-5ea66f13bf564d94a4c264b6185475b5 |
| Source note | uspto-grants-2013_10 |