Methanol → tert-butyl 4-(5-cyclopropyl-3-ethyl-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate

HRID 104251Notes

Reaction equation

HRID 104251 reaction equation
[CH3:37][OH:38].[CH:1]1([c:4]2[c:5]([N:24]3[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]3)[c:6]3[c:7]([n:8][cH:9]2)[n:10]([CH2:15][c:16]2[cH:17][cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]2)[n:11][c:12]3[C:13]#[CH:14])[CH2:2][CH2:3]1>>[CH:1]1([c:4]2[c:5]([N:24]3[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]3)[c:6]3[c:7]([n:8][cH:9]2)[n:10]([CH2:15][c:16]2[cH:17][cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]2)[n:11][c:12]3[CH2:13][CH3:14])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 887MethanolHCID 86647261tert-butyl 4-(5-cyclopropyl-3-ethynyl-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate

Product 1

HCID 68768039tert-butyl 4-(5-cyclopropyl-3-ethyl-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-f562b36466ac4b6cb5042452e306ebf9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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