HCID 70653939, compound → HCID 67105609, compound

Participants

Reaction Steps

A solution of crude 10 (4.5 mmol) in dichloromethane (80 mL) was treated with manganese dioxide (85%, 6 g, 15 equiv.) and this suspension was stirred at reflux for 6 hr. The solids were filtered out and washed with ethyl acetate. The solvent was removed in a rotary evaporator and the residue was chromatographed on silica (65 g) with 2% ethyl acetate in heptane (3 L). Pure 11 (1.2 g, 59%) was isolated.

Provenance & Evidence