Imidazole → HCID 11647526, compound

Participants

Reaction Steps

This material was prepared according to the procedure outlined above for 2-(N-imidazolyl)-7-hydroxy-3-(3,4,5-trimethoxybenzoyl)-6-methoxy-benzo[b]furan (entry 27, Table 1), above, except pyridine was used as the solvent in place of toluene, THF and triethylamine and pyrazole was used as the nucleophile in place of imidazole. 1H NMR (300 MHz, CDCl3) δ 7.82 (d, 1H, J=2.55 Hz), 7.65 (d, 1H, J=1.51 Hz), 7.18 (d, 1H, J=8.57 Hz), 7.01 (s, 2H, benzoyl Hs), 6.96 (d, 1H, J=8.61 Hz), 6.30 (t, 1H, J=1.88 Hz), 3.96 (s, 3H, OMe), 3.86 (s, 3H, OMe), 3.75 (s, 6H, 2×OMe).

Provenance & Evidence