HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-Nitro-5-(trifluoromethyl)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Nitro-5-(trifluoromethyl)benzoic acid | HCID 616602 | — |
| Product | 3-Nitro-5-(trifluoromethyl)benzoyl chloride | HCID 22608399 | — |
Reaction Steps
A solution of thionyl chloride (30 ml) and 3-nitro-5-(trifluoromethyl)benzoic acid (10 g) was heated to reflux for 2 h. The reaction mixture was concentrated under reduced pressure and azeotroped with toluene (10 ml—removed under reduced pressure) to afford 3-nitro-5-(trifluoromethyl)benzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557996B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-8c96f968b55f49029bd9be4cd9d70eef |
| Source note | uspto-grants-2013_10 |