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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1042736Generated: October 30, 2026

3-(Trifluoromethoxy)aniline → 4-Chloro-3-iodo-N-(3-(trifluoromethoxy)phenyl)benzamide

https://huagongshe.com/reaction/1042736

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethoxy)anilineHCID 73753—
Reactant4-Chloro-3-iodobenzoyl chlorideHCID 57349940—
Product4-Chloro-3-iodo-N-(3-(trifluoromethoxy)phenyl)benzamideHCID 59428035—

Reaction Steps

4-Chloro-3-iodo-N-(3-(trifluoromethoxy)phenyl)benzamide was synthesized from 3-(trifluoromethoxy)aniline and 4-chloro-3-iodobenzoylchloride according to the procedure described in Example 183, affording the title compound as a white solid. MS (M−H+) 439.8; Calculated for C14H8ClF3INO2: 441.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08557996B2
Source datasetuspto-grants-2013_10
ORD IDord-34dda95ffff946f08c0c5a9e2cd4fe00
Source noteuspto-grants-2013_10