HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → (2-(5-Bromo-2-chlorophenoxy)ethyl)(methyl)sulfane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-Chloroethyl methyl sulfide | HCID 10965 | — |
| Reactant | 5-Bromo-2-chlorophenol | HCID 820392 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (2-(5-Bromo-2-chlorophenoxy)ethyl)(methyl)sulfane | HCID 67317126 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
5-Bromo-2-chlorophenol (500 mg, 2410 μmol) and (2-chloroethyl)(methyl)sulfane (262 μl, 2651 μmol) were combined with cesium carbonate (942 mg, 2892 μmol) in DMF and heated to 100° C. for 2 h. The mixture was then filtered and purified using reverse phase chromatography. This purified material was carried forward to the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08557816B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-2aa2ff08953447e49fb9e6a08613eaf6 |
| Source note | uspto-grants-2013_10 |