Nitric Acid → 1,4-Dinitro-1H-imidazole

HRID 1042949Notes

Reaction equation

HRID 1042949 reaction equation
[N+:1]([C:4]1[N:5]=[CH:6][NH:7][CH:8]=1)([O-:3])=[O:2].[N+:9]([O-])([OH:11])=[O:10].C(OC(=O)C)(=O)C>C(O)(=O)C>[N+:9]([N:7]1[CH:8]=[C:4]([N+:1]([O-:3])=[O:2])[N:5]=[CH:6]1)([O-:11])=[O:10]

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 7918Acetic AnhydrideHCID 178526856HCID 178526856, compound

Product 1

HCID 51694961,4-Dinitro-1H-imidazole

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Forthly, 4-Nitroimidazole is dissolved in acetic acid and then a nitric acid having a high concentration as much as 80 mass % or more and acetic anhydride are added thereto to produce 1,4-dinitroimidazole in any of the processes described in the documents mentioned above.

Sources & evidence

ORD record
ord-ace324726c084d3aafaca88820b0a6a8
Source dataset
uspto-grants-2013_10
Patent number
US08558005B2

Reaction notes

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