Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Chloro-3-nitrobenzenesulfonamide | HCID 7324 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-(Aminomethyl)oxan-4-amine | HCID 43608727 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67126605 | HCID 67126605 | — |
Reaction Steps
A mixture of 4-chloro-3-nitrobenzenesulfonamide, 4-(aminomethyl)tetrahydro-2H-pyran-4-amine, hydrochloric acid and triethylamine in dioxane (10 mL) was heated at 110° C. overnight. After cooling, the mixture was diluted with water (10 mL), and filtered.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08557983B2 |
|---|
| Source dataset | uspto-grants-2013_10 |
|---|
| ORD ID | ord-1c33dca907094ff3b418c6c1c05a23d0 |
|---|
| Source note | uspto-grants-2013_10 |
|---|
