Triacetoxyperiodinane → Benzyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate

Participants

Reaction Steps

To a solution of EXAMPLE 391C (23.66 g) in dichloromethane (350 mL) was added Dess-Martin Periodinane (33.1 g). The mixture was stirred overnight. The mixture was diluted with ethyl acetate (600 mL) and washed with 2N aqueous NaOH, water, and brine. After drying over Na2SO4, the mixture was filtered and concentrated to provide the title compound.

Provenance & Evidence