Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Isoamyl Nitrite | HCID 8053 | — |
| Reactant | Potassium Acetate | HCID 517044 | — |
| Reactant | HCID 67227617 | HCID 67227617 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 67226405 | HCID 67226405 | — |
Reaction Steps
A mixture of EXAMPLE 446A (1.0 g), acetic anhydride (0.734 mL), and potassium acetate (0.428 g) in toluene (20 mL) was stirred at room temperature for three hours. To the flask was added isoamyl nitrite (1.03 mL). The reaction mixture was heated at 80° C. for 16 hours. The solvent was removed, and the residue was purified by flash column chromatography on silica gel to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08557983B2 |
|---|
| Source dataset | uspto-grants-2013_10 |
|---|
| ORD ID | ord-b4e2f5db029141d9980f1cc70de6d4ca |
|---|
| Source note | uspto-grants-2013_10 |
|---|
