Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → N-((6-chloropyridin-3-yl)methyl)ethenamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Ethylamine | HCID 6341 | — |
| 반응물 | 2-Chloro-5-(chloromethyl)pyridine | HCID 155479 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | N-((6-chloropyridin-3-yl)methyl)ethenamine | HCID 86658943 | — |
반응 단계
To a solution of aqueous ethylamine, an appropriate amount of acetonitrile is, added. Then 2-chloro-5-(chloromethyl)pyridine in acetonitrile is added dropwise in ice bath. The reaction is monitored by TLC. After completion, the mixture is added large amount of water, extracted by DCM, dried, filtered and evaporated to obtain N-((6-chloropyridin-3-yl)methyl)ethenamine as oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08563546B2 |
| 출처 데이터셋 | uspto-grants-2013_10 |
| ORD ID | ord-f0411e4723034c8c9aa7d735ae19cd87 |
| 출처 메모 | uspto-grants-2013_10 |