HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-chloro-N-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)acetamide → HCID 71577722, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-chloro-N-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)acetamide | HCID 68207026 | — |
| Reactant | HCID 86685914 | HCID 86685914 | — |
| Product | HCID 71577722 | HCID 71577722 | 27.6% |
Reaction Steps
Similar to the manipulation of example 1, with (S)-2-chloro-N-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)acetamide (130 mg, 0.50 mmol) and 4-(4-(2-(2,2,2-trifluoroethoxy)ethoxy)phenoxy)piperidine (319 mg, 1.0 mmol) as crude materials, 75 mg title compound was generated and yield was 27%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563547B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-fef0c2b5aa534a3a9d28f3a689bc5acd |
| Source note | uspto-grants-2013_10 |