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HRID1043571

反应详情

EQUATION

反应方程式

HRID 1043571 的结构方程式

REACTANTS

反应物

2
反应SMILES：CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C
HCID45480186

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

C13H17BN2O2

反应SMILES：CC(C)(O)C1CCN(Cc2ccc3nc(Cl)nc(N4CCOCC4)c3n2)CC1
HCID58404970

未命名化合物

PRODUCTS

产物

1
反应SMILES：CC(C)(O)C1CCN(Cc2ccc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3n2)CC1
HCID53378156

未命名化合物

PROCEDURE

实验过程

2-(1-((2-chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-ol from Example 8 (88 mg) was reacted with 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole via General Procedure A to produce 29.6 mg of 110 following reverse phase hplc purification. MS (Q1) 488.3 (M)+

WORKUP

后处理

  1. customto produce
  2. custom29.6 mg of 110 following reverse phase hplc purification