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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1043598생성일: 2026년 10월 26일

4-(6-(Bromomethyl)-2-chloropyrido[3,2-D]pyrimidin-4-YL)morpholine → 4-(1-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)azetidin-3-yl)piperazin-2-one

https://huagongshe.com/reaction/1043598

반응식

참여 물질

역할이름HCID투입량
반응물4-(6-(Bromomethyl)-2-chloropyrido[3,2-D]pyrimidin-4-YL)morpholineHCID 58404978—
반응물4-(Azetidin-3-yl)piperazin-2-oneHCID 59606145—
생성물4-(1-((2-Chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)azetidin-3-yl)piperazin-2-oneHCID 58405021—

반응 단계

4-(6-(bromomethyl)-2-chloropyrido[3,2-d]pyrimidin-4-yl)morpholine 7 (0.201 g) was reacted with 4-(azetidin-3-yl)piperazin-2-one via General Procedure B to afford 0.18 g 4-(1-((2-chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)azetidin-3-yl)piperazin-2-one.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08563540B2
출처 데이터셋uspto-grants-2013_10
ORD IDord-ecd275c52cb84cab9ad4d03c97824ebd
출처 메모uspto-grants-2013_10