HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Oxetan-3-yl)piperidine → 4-(2-Chloro-6-((4-(oxetan-3-yl)piperidin-1-yl)methyl)pyrido[3,2-d]pyrimidin-4-yl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Oxetan-3-yl)piperidine | HCID 55264245 | — |
| Reactant | 4-(6-(Bromomethyl)-2-chloropyrido[3,2-D]pyrimidin-4-YL)morpholine | HCID 58404978 | — |
| Product | 4-(2-Chloro-6-((4-(oxetan-3-yl)piperidin-1-yl)methyl)pyrido[3,2-d]pyrimidin-4-yl)morpholine | HCID 58405033 | — |
Reaction Steps
4-(6-(Bromomethyl)-2-chloropyrido[3,2-d]pyrimidin-4-yl)morpholine 7 (0.199 g) was reacted with 4-(oxetan-3-yl)piperidine via General Procedure B to afford 0.11 g 4-(2-chloro-6-((4-(oxetan-3-yl)piperidin-1-yl)methyl)pyrido[3,2-d]pyrimidin-4-yl)morpholine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563540B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-560349d890e4479f84d57d715165215d |
| Source note | uspto-grants-2013_10 |