HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(tert-Butyldimethylsilyl)-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole → HCID 53378901, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(tert-Butyldimethylsilyl)-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole | HCID 57506725 | — |
| Reactant | HCID 58404955 | HCID 58404955 | — |
| Product | HCID 53378901 | HCID 53378901 | — |
Reaction Steps
N-((2-chloro-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)isobutyramide (0.125 g) was reacted with 1-(tert-butyldimethylsilyl)-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole via General Procedure A to produce 14.5 mg of 147 following reverse phase HPLC purification. MS (Q1) 449.2 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563540B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-3f0753df7247433a8d453fd388add9b3 |
| Source note | uspto-grants-2013_10 |