HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58147973, compound → HCID 136184191, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58147973 | HCID 58147973 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 136184191 | HCID 136184191 | 93% |
Reaction Steps
A solution of 3-Benzyloxy-2-[5-(3-chloro-4-fluoro-benzyl)-thiazol-2-yl]-9-(3-methyl-2-oxo-imidazolidin-1-yl)-7-morpholin-4-yl-pyrido[1,2-a]pyrimidin-4-one (50 mg, 0.076 mmol) in trifluoroacetic acid (1 ml) was refluxed for 3 h. Then trifluoroacetic acid was removed under reduced pressure and MeOH (3 ml) was added. The resulting precipitate was collected by filtration and washed with MeOH to give title compound (40 mg, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563562B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-cea9f0c8abab45d48eec63efc8de49dc |
| Source note | uspto-grants-2013_10 |