HuagongsheHuagongshe Chemistry Print Report · For research reference only
D-Tartaric acid → (R)-((R)-quinuclidin-3-yl) 2-(4-fluorophenylamino)-2-phenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | D-Tartaric acid | HCID 439655 | — |
| Reactant | HCID 58556923 | HCID 58556923 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | (R)-((R)-quinuclidin-3-yl) 2-(4-fluorophenylamino)-2-phenylacetate | HCID 59401133 | — |
Reaction Steps
(2S,3S)-2,3-dihydroxysuccinic acid (0.23 g, 1.52 mmol) was added to a suspension of (R)-quinuclidin-3-yl 2-(4-fluorophenylamino)-2-phenylacetate (1.08 g, 3.05 mmol) in acetone (140 ml). The resulting mixture was heated at reflux and then allowed to cool at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563577B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-0d923cb5efb54b8e8f8e798f744bc5f7 |
| Source note | uspto-grants-2013_10 |