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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044083Generated: October 30, 2026

Cyclopentanone → Ethyl1-[(cyclopentylamino)methyl]cyclopropane-1-carboxylate

https://huagongshe.com/reaction/1044083

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentanoneHCID 8452—
ReactantSodium AcetateHCID 517045—
ReactantSodium triacetoxyborohydrideHCID 5049666—
ReactantEthyl 1-(aminomethyl)cyclopropanecarboxylateHCID 11480505—
SolventDichloromethaneHCID 6344—
ProductEthyl1-[(cyclopentylamino)methyl]cyclopropane-1-carboxylateHCID 58153972—

Reaction Steps

Reaction of 1-aminomethyl-cyclopropanecarboxylic acid ethyl ester with cyclopentanone, sodium acetate and sodium triacetoxyborohydride in DCM gave 1-cyclopentylaminomethyl-cyclopropanecarboxylic acid ethyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563542B2
Source datasetuspto-grants-2013_10
ORD IDord-e0dec8468c76468db660f04bbe53bbe7
Source noteuspto-grants-2013_10