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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044085Generated: October 30, 2026

Cyclopentanone → Ethyl 3-(cyclopentylamino)-2,2-dimethylpropanoate

https://huagongshe.com/reaction/1044085

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentanoneHCID 8452—
ReactantEthyl 3-amino-2,2-dimethylpropanoateHCID 421529—
ReactantSodium AcetateHCID 517045—
ReactantSodium triacetoxyborohydrideHCID 5049666—
SolventDichloromethaneHCID 6344—
ProductEthyl 3-(cyclopentylamino)-2,2-dimethylpropanoateHCID 57969950—

Reaction Steps

Reaction of 3-amino-2,2-dimethyl-propionic acid ethyl ester with cyclopentanone, sodium acetate and sodium triacetoxyborohydride in DCM gave 3-Cyclopentylamino-2,2-dimethyl-propionic acid ethyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563542B2
Source datasetuspto-grants-2013_10
ORD IDord-48c90496f5da4b2ab229632f0761e61f
Source noteuspto-grants-2013_10