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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044086Generated: October 30, 2026

Potassium Carbonate → Ethyl3-[(2-chloro-5-nitro-pyrimidin-4-yl)-cyclopentyl-amino]-2,2-dimethyl-propanoate

https://huagongshe.com/reaction/1044086

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2,4-Dichloro-5-nitropyrimidineHCID 521266—
ReactantEthyl 3-(cyclopentylamino)-2,2-dimethylpropanoateHCID 57969950—
SolventAcetoneHCID 180—
ProductEthyl3-[(2-chloro-5-nitro-pyrimidin-4-yl)-cyclopentyl-amino]-2,2-dimethyl-propanoateHCID 58153872—

Reaction Steps

Reaction of 3-cyclopentylamino-2,2-dimethyl-propionic acid ethyl ester with 2,4-dichloro-5-nitropyrimidine and K2CO3 in acetone gave 3-[(2-Chloro-5-nitro-pyrimidin-4-yl)-cyclopentyl-amino]-2,2-dimethyl-propionic acid ethyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563542B2
Source datasetuspto-grants-2013_10
ORD IDord-0d9edfc509074e1381bb921e8abf252b
Source noteuspto-grants-2013_10