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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044090Generated: November 1, 2026

Cyclopentanone → 1-Cyclopentylaminomethyl-cyclobutanecarboxylic acid methyl ester

https://huagongshe.com/reaction/1044090

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentanoneHCID 8452—
ReactantSodium AcetateHCID 517045—
ReactantSodium triacetoxyborohydrideHCID 5049666—
ReactantMethyl 1-(Aminomethyl)cyclobutanecarboxylateHCID 25918829—
SolventDichloromethaneHCID 6344—
Product1-Cyclopentylaminomethyl-cyclobutanecarboxylic acid methyl esterHCID 58154148—

Reaction Steps

Reaction of 1-aminomethyl-cyclobutanecarboxylic acid methyl ester with cyclopentanone, sodium acetate and sodium triacetoxyborohydride in DCM gave 1-cyclopentylaminomethyl-cyclobutanecarboxylic acid methyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563542B2
Source datasetuspto-grants-2013_10
ORD IDord-e7bbfd8e94204d349f9dc8b835864779
Source noteuspto-grants-2013_10