HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-{[(2-Chloro-5-nitro-pyrimidin-4-yl)-cyclopentyl-amino]-methyl}-cyclobutanecarboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,4-Dichloro-5-nitropyrimidine | HCID 521266 | — |
| Reactant | 1-Cyclopentylaminomethyl-cyclobutanecarboxylic acid methyl ester | HCID 58154148 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-{[(2-Chloro-5-nitro-pyrimidin-4-yl)-cyclopentyl-amino]-methyl}-cyclobutanecarboxylic acid methyl ester | HCID 58153885 | — |
Reaction Steps
Reaction of 1-cyclopentylaminomethyl-cyclobutanecarboxylic acid methyl ester with 2,4-dichloro-5-nitropyrimidine and K2CO3 in acetone gave 1-{[(2-chloro-5-nitro-pyrimidin-4-yl)-cyclopentyl-amino]-methyl}-cyclobutanecarboxylic acid methyl ester
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563542B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-09938e5607e243cbb4866df92ae31e61 |
| Source note | uspto-grants-2013_10 |