HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-methylpyridin-2-yl)-5-nitro-2H-indazole → HCID 67126077, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-methylpyridin-2-yl)-5-nitro-2H-indazole | HCID 67126051 | — |
| Reactant | HCID 67126947 | HCID 67126947 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67126077 | HCID 67126077 | — |
Reaction Steps
The mixture of 1-(5-methylpyridin-2-yl)-5-nitro-1H-indazole and 2-(5-methylpyridin-2-yl)-5-nitro-2H-indazole was dissolved in EtOH (20 mL), and 10% Pd/C (250 mg) was added. Under H2 atmosphere, the mixture was stirred at room temperature for 12 h, filtered and concentrated in vacuo. The residue was chromatographed on silica gel eluting with AcOEt/Hexane to give the title compound (61 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563575B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-93be2dfdb74e44a5a07835a198b9c7a1 |
| Source note | uspto-grants-2013_10 |