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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044327Generated: November 1, 2026

Phenethylamine → 3-(p-Tolyl)-1,4-dihydro-4-oxo-5-phenethylamino-1,6-naphthyridine

https://huagongshe.com/reaction/1044327

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenethylamineHCID 1001—
Reactant4-ChloroanilineHCID 7812—
ReactantEthyl (4-chlorophenyl)acetateHCID 84177—
ReactantBenzeneacetic acid, 4-fluoro-, ethyl esterHCID 3013910—
Reactant3-(4-Fluorophenyl)-1,4-dihydro-4-oxo-5-(4-chlorophenylamino)-1,6-naphthyridineHCID 46847902—
Product3-(p-Tolyl)-1,4-dihydro-4-oxo-5-phenethylamino-1,6-naphthyridineHCID 46847609—

Reaction Steps

3-(4-Fluorophenyl)-1,4-dihydro-4-oxo-5-(4-chlorophenylamino)-1,6-naphthyridine The title compound was prepared as described in Example 1 above except that ethyl (4-chlorophenyl)acetate was replaced with ethyl (4-fluorophenyl)acetate and phenethylamine was replaced with 4-chloroaniline. MS 366 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563579B2
Source datasetuspto-grants-2013_10
ORD IDord-67032961cd164c3d8ee46c41186b000e
Source noteuspto-grants-2013_10