HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophenol → HCID 14791622, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3,3-Dimethylbutanoyl chloride | HCID 81514 | — |
| Reactant | Isohexane ethyl acetate | HCID 21882781 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 14791622 | HCID 14791622 | 90.3% |
Reaction Steps
3,3-Dimethylbutanoyl chloride (695 μL, 5.0 mmol) in 15 mL toluene was added to a solution of triethylamine (0.70 mL, 5.0 mmol) and thiophenol (0.51 mL, 5.0 mmol) in 10 mL toluene. Reaction monitoring was accomplished by TLC: iso-hexane/ethyl acetate 25:1, Rf=0.63. Workup yielded 941 mg (90%) S-phenyl 3,3-dimethylbutanethioate 5 as pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563598B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-446b2a267cf34656964ceba5ba71bb0e |
| Source note | uspto-grants-2013_10 |