HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophenol → S-Phenyl 2-(2-naphthyl)ethanethioate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-(2-Naphthyl)acetyl chloride | HCID 588115 | — |
| Reactant | Isohexane ethyl acetate | HCID 21882781 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | S-Phenyl 2-(2-naphthyl)ethanethioate | HCID 86656471 | 90% |
Reaction Steps
2-(2-Naphthyl)acetyl chloride (308 mg, 1.5 mmol) in 4.5 mL toluene was added to a solution of triethylamine (0.21 mL, 1.5 mmol) and thiophenol (153 μL, 1.5 mmol) in 3 mL toluene. Reaction monitoring was accomplished by TLC: iso-hexane/ethyl acetate 25:1, Rf=0.33. Workup yielded 376 mg (90%) S-phenyl 2-(2-naphthyl)ethanethioate 9 as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563598B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-72f8aa65196b4fac9589f9473775982e |
| Source note | uspto-grants-2013_10 |