3-(Piperidin-4-yl)propan-1-ol hydrochloride → HCID 54239091, compound

HRID 1044861Notes

Reaction equation

HRID 1044861 reaction equation
[CH2:1]([N:3]1[CH2:8][CH2:7][CH:6]([CH2:9][CH2:10]O)[CH2:5][CH2:4]1)[CH3:2].Cl.N1CCC(CC[CH2:21][OH:22])CC1>>[CH2:1]([N:3]1[CH2:4][CH2:5][CH:6]([CH2:9][CH2:10][CH2:21][OH:22])[CH2:7][CH2:8]1)[CH3:2]

Participants

3

Reactant 2

HCID 184257203-(Piperidin-4-yl)propan-1-ol hydrochlorideHCID 21702781HCID 21702781, compound

Product 1

HCID 54239091HCID 54239091, compound

Procedure

Prepared similarly to Intermediate 20 from 3-(4-piperidinyl)-1-propanol hydrochloride. 1H NMR (400 MHz, DMSO-d6) δ ppm 0.96 (t, J=7.2 Hz, 3H) 1.01-1.23 (m, 5H) 1.36-1.45 (m, 2H) 1.56-1.63 (m, 2H) 1.72-1.81 (m, 2H) 2.22-2.29 (m, 2H) 2.73 (s, 17H residual DMF) 2.81 (d, J=11.54 Hz, 2H) 2.86-2.92 (m, 18H residual DMF) 3.30-3.39 (m, 3H) 4.30-4.36 (m, 1H) 7.95 (s, 8H residual DMF)

Sources & evidence

ORD record
ord-3f9a2ede381249ec95ad346bc36d2427
Source dataset
uspto-grants-2013_10
Patent number
US08563717B2

Reaction notes

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