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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044874Generated: October 31, 2026

Phenylmethyl 2-{2-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylate → Phenylmethyl 3-{2-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]ethyl}1-piperidinecarboxylate

https://huagongshe.com/reaction/1044874

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethyl 2-{2-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylateHCID 58306137—
ReactantBenzyl 3-(2-bromoethyl)piperidine-1-carboxylateHCID 58306150—
ReactantHCID 178450370HCID 178450370—
ProductPhenylmethyl 3-{2-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]ethyl}1-piperidinecarboxylateHCID 58306107—

Reaction Steps

Prepared similarly to Intermediate 27 from phenylmethyl 3-(2-bromoethyl)-1-piperidinecarboxylate and 2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine trifluoroacetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-48db21ff1c824843bcccd70708e31808
Source noteuspto-grants-2013_10