Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044887Generated: November 2, 2026

Iodoethane → 9-[3-(1-Ethyl-3-piperidinyl)propyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine

https://huagongshe.com/reaction/1044887

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactant9-[2-(1-Ethyl-3-piperidinyl)ethyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amineHCID 58306212—
Reactant2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[3-(3-piperidinyl)propyl]-9H-purin-6-amineHCID 58306271—
Product9-[3-(1-Ethyl-3-piperidinyl)propyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amineHCID 58306249—

Reaction Steps

Prepared similarly to Intermediate 46 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9-[3-(3-piperidinyl)propyl]-9H-purin-6-amine and 2-iodoethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-db46e6f0299e4b548d971f5755defa39
Source noteuspto-grants-2013_10