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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044898Generated: October 31, 2026

Phenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylate → Phenylmethyl 3-{5-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]pentyl}-1-piperidinecarboxylate

https://huagongshe.com/reaction/1044898

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306132—
ReactantPhenylmethyl 3-(5-bromopentyl)-1-piperidinecarboxylateHCID 58306229—
ReactantHCID 178450370HCID 178450370—
ProductPhenylmethyl 3-{5-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]pentyl}-1-piperidinecarboxylateHCID 58306261—

Reaction Steps

Prepared similarly to Intermediate 31 from 2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine trifluoroacetate and phenylmethyl 3-(5-bromopentyl)-1-piperidinecarboxylate. LCMS (System B): tRET=3.28 min; MH+ 525

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-861b5cea2f4c40fe9c9d70d463f44d3c
Source noteuspto-grants-2013_10