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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044908Generated: October 31, 2026

Benzyl 4-(2-bromoethyl)piperidine-1-carboxylate → phenylmethyl 4-{[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylate

https://huagongshe.com/reaction/1044908

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl 4-(2-bromoethyl)piperidine-1-carboxylateHCID 11056468—
ReactantPhenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306132—
ReactantHCID 178450370HCID 178450370—
Productphenylmethyl 4-{[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylateHCID 58306071—

Reaction Steps

Prepared similarly to Intermediate 31 from 2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine trifluoroacetate and phenylmethyl 4-(2-bromoethyl)-1-piperidinecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-996d06403b4d468b83d5d4fecf0a3514
Source noteuspto-grants-2013_10