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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044912Generated: November 1, 2026

Phenylmethyl 4-{2-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylate → 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1044912

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethyl 4-{2-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylateHCID 58306076—
Reactant2-(Butyloxy)-8-(methyloxy)-9-[3-(2-piperidinyl)propyl]-9H-purin-6-amineHCID 58306184—
Product2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amineHCID 58306232—

Reaction Steps

Prepared similarly to Intermediate 32 from phenylmethyl 4-{2-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]ethyl}-1-piperidinecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-5ee866c33f6d49d4bf2e1e7e8b559f03
Source noteuspto-grants-2013_10