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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044918Generated: November 1, 2026

Phenylmethyl 4-{3-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylate → 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[3-(4-piperidinyl)propyl]-9H-purin-6-amine

https://huagongshe.com/reaction/1044918

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethyl 4-{3-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306146—
Reactant2-(Butyloxy)-8-(methyloxy)-9-[3-(2-piperidinyl)propyl]-9H-purin-6-amineHCID 58306184—
Product2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[3-(4-piperidinyl)propyl]-9H-purin-6-amineHCID 58306182—

Reaction Steps

Prepared similarly to Intermediate 32 from phenylmethyl 4-{3-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-5cac281e1c3c43bd82c9d5e45307d656
Source noteuspto-grants-2013_10