HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylmethyl 4-{4-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]butyl}-1-piperidinecarboxylate → 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[4-(4-piperidinyl)butyl]-9H-purin-6-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylmethyl 4-{4-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]butyl}-1-piperidinecarboxylate | HCID 58306080 | — |
| Reactant | 2-(Butyloxy)-8-(methyloxy)-9-[3-(2-piperidinyl)propyl]-9H-purin-6-amine | HCID 58306184 | — |
| Product | 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-[4-(4-piperidinyl)butyl]-9H-purin-6-amine | HCID 58306057 | — |
Reaction Steps
Prepared similarly to Intermediate 32 from phenylmethyl 4-{4-[6-amino-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-9-yl]butyl}-1-piperidinecarboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563717B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-4157421894944032abaa8025618626df |
| Source note | uspto-grants-2013_10 |