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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044930Generated: October 31, 2026

Phenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylate → Phenylmethyl 4-{5-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]pentyl}-1-piperidinecarboxylate

https://huagongshe.com/reaction/1044930

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306132—
ReactantPhenylmethyl 4-(5-bromopentyl)-1-piperidinecarboxylateHCID 58306239—
ReactantHCID 178450370HCID 178450370—
ProductPhenylmethyl 4-{5-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]pentyl}-1-piperidinecarboxylateHCID 58306175—

Reaction Steps

Prepared similarly to Intermediate 31 from 2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine trifluoroacetate and phenylmethyl 4-(5-bromopentyl)-1-piperidinecarboxylate. LCMS (System B): tRET=3.31 min; MH+ 525

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-68f6533690d04170b2ba30fd27f100c2
Source noteuspto-grants-2013_10