6-(4-Piperidinyl)-1-hexanol → Phenylmethyl 4-(6-hydroxyhexyl)-1-piperidinecarboxylate
Reaction equation
OCCCCC[CH:7]1[CH2:12][CH2:11][CH2:10][N:9]([C:13]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:14])[CH2:8]1.N1CCC([CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][OH:35])CC1>>[OH:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH:12]1[CH2:7][CH2:8][N:9]([C:13]([O:15][CH2:16][C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[O:14])[CH2:10][CH2:11]1Participants
3
Procedure
Prepared similarly to Intermediate 64 from 6-(4-piperidinyl)-1-hexanol. LCMS (System B): tRET=3.00 min; MH+ 320
Workup
- custom=3.00 min
Sources & evidence
- ORD record
- ord-092d809479c24a39befb8bd40a2d9632
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08563717B2
Reaction notes
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