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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044963Generated: November 1, 2026

Isobutyl iodide → 6-Amino-2-(butyloxy)-9-{[1-(2-methylpropyl)-3-piperidinyl]methyl}-7,9-dihydro-8H-purin-8-one

https://huagongshe.com/reaction/1044963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsobutyl iodideHCID 10556—
Reactant2-butoxy-8-methoxy 9-(piperidin-3-ylmethyl)-9H-purin-6-amineHCID 58306241—
Product6-Amino-2-(butyloxy)-9-{[1-(2-methylpropyl)-3-piperidinyl]methyl}-7,9-dihydro-8H-purin-8-oneHCID 67233630—

Reaction Steps

Prepared similarly to Example 24 from 2-(butyloxy)-8-(methyloxy)-9-(3-piperidinylmethyl)-9H-purin-6-amine and 1-iodo-2-methylpropane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-b7c97b26c03846929ce046294e5dbab3
Source noteuspto-grants-2013_10